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Activists of the Islamic Party's Ennahda as they wave is flags during a demonstration in Tunis Saturday Feb 9, 2013. Several thousand supporters of Tunisia's ruling moderate Islamist party rallied in the capital in a pro-government demonstration Saturday, a day after the funeral of an assassinated opposition politician. The ruling Ennahda party had called for a show of support for the constitutional assembly, whose work on a new constitution suffered a severe setback after the killing of Chokri Belaid on Feb. 6, 2013 when leftist parties withdrew their participation. Protesters hurled insults at France, accusing the former colonial ruler of interfering in the North African country's politics. ( AP Photo/Hassene Dridi)
Activists of the Islamic Party's Ennahda as they wave is flags during a demonstration in Tunis Saturday Feb 9, 2013. Several thousand supporters of Tunisia's ruling moderate Islamist party rallied in the capital in a pro-government demonstration Saturday, a day after the funeral of an assassinated opposition politician. The ruling Ennahda party had called for a show of support for the constitutional assembly, whose work on a new constitution suffered a severe setback after the killing of Chokri Belaid on Feb. 6, 2013 when leftist parties withdrew their participation. Protesters hurled insults at France, accusing the former colonial ruler of interfering in the North African country's politics. ( AP Photo/Hassene Dridi)
Protesters gather during a demonstration in Tunis Saturday Feb 9, 2013. Several thousand supporters of Tunisia's ruling moderate Islamist party rallied in the capital in a pro-government demonstration Saturday, a day after the funeral of an assassinated opposition politician. The ruling Ennahda party had called for a show of support for the constitutional assembly, whose work on a new constitution suffered a severe setback after the killing of Chokri Belaid on Feb. 6, 2013 when leftist parties withdrew their participation. Protesters hurled insults at France, accusing the former colonial ruler of interfering in the North African country's politics. ( AP Photo/Hassene Dridi)
TUNIS, Tunisia (AP) ? Calm is returning to the streets of Tunisia's capital, even as pressure is growing on the governing Islamists to find a solution to the country's biggest crisis since it set off the Arab Spring uprisings two years ago.
The killing of a Tunisian opposition leader last week brought protests against a government accused of pandering to extremists. The prime minister wants to appoint a new government of technocrats to ease tensions.
But his Ennahda party rejects the idea. Ennahda's governing committee is meeting Sunday to discuss it, amid signs of a growing split between party moderates and hard-liners.
After three days of street violence, the streets in the capital Tunis are relatively quiet Sunday, under the watchful eye of riot police.
Associated PressJordyn Wieber michael phelps Kerri Strug Ledecky Nadia Comaneci Rebecca Soni Snoop Lion
AMMAN (Reuters) - Syrian government jets bombarded the Damascus ring road on Thursday in a bid to halt a rebel advance which threatens President Bashar al-Assad's hold on the capital, insurgent commanders and opposition activists said.
Warplanes fired rockets at southern parts of the route where rebels have spent the past 36 hours overrunning army positions and road blocks encircling the heart of the city, the site of key state security and intelligence installations.
Assad, battling to crush a 22-month-old revolt in which 60,000 people have died, has lost control of large parts of the country but his forces, backed by air power, have so far kept rebels away from the centre of Damascus.
World powers fear the conflict - the longest and deadliest of the uprisings that started spreading through the Arab world two years ago - could envelop Syria's neighbors, further destabilizing an already explosive region.
"The regime really wants its positions on the ring road back. It is a major defense line for the capital," Aby Ghazi, a rebel commander based in the eastern suburb of Irbreen told Reuters.
Ghazi said the rebels have reached the edges of the city's main Abbaside Square where the Syrian military had turned a football stadium into barracks.
Authorities have banned most independent media from the country, making it difficult to verify events on the ground.
Units of Assad's elite Republican Guard based on the imposing Qasioun Mountain overlooking the capital fired artillery rounds and rockets at Jobar, an eastern neighborhood bordering the square, and at the ring road, rebel and activist sources said.
Damascus residents, long accustomed to the sounds of war, said Thursday's shelling was some of the heaviest they had heard.
"They've gone insane. All of them. They're insane," one central Damascus resident said by telephone.
DEATHCOUNT
U.S. State Department spokeswoman Victoria Nuland said the Assad government had responded to the rebel offensive by "indiscriminately shelling unarmed civilians".
"This violates every tenet of international law, and we call for the perpetrators to be held accountable," she said.
Neither side has gained a clear military advantage in the civil war pitting mostly Sunni Muslim rebels against security forces dominated by Assad's minority Alawite sect, an offshoot of Shi'ite Islam.
Assad has framed the revolt as a foreign-backed conspiracy and blames the West and Sunni Gulf states.
State media said on Thursday the army had pushed back rebels from Jobar and other eastern districts.
It added six people, including a woman and three children, were killed by rebel mortar fire on a bus station in the north-eastern district of al-Qaboun on Thursday, with several other people seriously wounded.
But Fidaa Mohammad, an activist in the district, said those killed were members of the 'popular committees', a militia set up by the ruling Baath Party's intelligence apparatus to help Assad maintain his grip on the capital.
Activists said 46 people had died on Thursday, mostly from heavy army bombardment on the contested neighborhoods of Jobar and Zamalka which are near compounds housing Alawite forces.
A retired military officer in Damascus said the shelling of rebel areas was hitting civilians and fighters indiscriminately.
The army "stand hundreds of meters away and fire shells. And the shells fall on anyone. Women and families and anybody. Where is the courage in that," he added.
One rebel commander told Reuters the insurgents were not trying to take the capital with the current push.
"The objective is to take out the sniper positions and fortifications that form part of the regime's defense line on Damascus, not to advance too quickly without having the proper support," said Captain Islam Alloush of the Liwa al-Islam rebel unit.
Another opposition activist in Damascus said the offensive was being led by Sunni officers who had defected from the army and wanted to cut Assad's command and control lines from the centre of the city to its outskirts.
The rebels are using anti-aircraft guns, mortar rounds and armored vehicles captured from Assad's forces over the past few months, according to opposition sources.
Many parents took their children out of Damascus schools early on Thursday and the acrid, stinging smell of explosives hung in the air, forcing some people to keep their windows closed.
Video footage, that could not be verified independently showed rebels inspecting several bodies identified as government soldiers and pro-Assad militiamen killed in fighting on Thalatheen street, a main Damascus thoroughfare straddling the southern rebel-held district of Hajar al-Aswad.
The rundown area, home to tens of thousands of refugees from the Israeli-occupied Golan Heights, is close to the southern entrance of the capital and the main highway to the city of Deraa and the Jordanian border.
(Editing by Andrew Heavens)
Source: http://news.yahoo.com/syrian-rebels-battle-army-control-damascus-districts-095458773.html
Feb. 6, 2013 ? A tiny capsule invented at a UCLA lab could go a long way toward improving cancer treatment.
Devising a method for more precise and less invasive treatment of cancer tumors, a team led by researchers from the UCLA Henry Samueli School of Engineering and Applied Science has developed a degradable nanoscale shell to carry proteins to cancer cells and stunt the growth of tumors without damaging healthy cells.
In a new study, published online Feb. 1 in the peer-reviewed journal Nano Today, a group led by Yi Tang, a professor of chemical and biomolecular engineering and a member of the California NanoSystems Institute at UCLA, reports developing tiny shells composed of a water-soluble polymer that safely deliver a protein complex to the nucleus of cancer cells to induce their death. The shells, which at about 100 nanometers are roughly half the size of the smallest bacterium, degrade harmlessly in non-cancerous cells.
The process does not present the risk of genetic mutation posed by gene therapies for cancer, or the risk to healthy cells caused by chemotherapy, which does not effectively discriminate between healthy and cancerous cells, Tang said.
"This approach is potentially a new way to treat cancer," said Tang. "It is a difficult problem to deliver the protein if we don't use this vehicle. This is a unique way to treat cancer cells and leave healthy cells untouched."
The cell-destroying material, apoptin, is a protein complex derived from an anemia virus in birds. This protein cargo accumulates in the nucleus of cancer cells and signals to the cell to undergo programmed self-destruction.
The polymer shells are developed under mild physiological conditions so as not to alter the chemical structure of the proteins or cause them to clump, preserving their effectiveness on the cancer cells.
Tests done on human breast cancer cell lines in laboratory mice showed significant reduction in tumor growth.
"Delivering a large protein complex such as apoptin to the innermost compartment of tumor cells was a challenge, but the reversible polymer encapsulation strategy was very effective in protecting and escorting the cargo in its functional form," said Muxun Zhao, lead author of the research and a graduate student in chemical and biomolecular engineering at UCLA.
Tang's group continues to research ways of more precisely targeting tumors, prolonging the circulation time of the capsules and delivering other highly sought-after proteins to cancer cells.
The research team also included former UCLA Engineering student Zhen Gu, now an assistant professor in the joint biomedical engineering department at the University of North Carolina at Chapel Hill and North Carolina State University, and University of Southern California researchers including graduate student Biliang Hu, postdoctoral scholar Kye-Il Joo and associate professor Pin Wang.
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The above story is reprinted from materials provided by University of California - Los Angeles. The original article was written by Bill Kisliuk.
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Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/genes/~3/aiAuB-2vX5Q/130206141649.htm
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LAS VEGAS -- MGM Resorts International is asking the Nevada Supreme Court to speed up a decision that's holding up the demolition of a flawed hotel tower on the Las Vegas Strip.
MGM filed a brief Wednesday asking the court to expedite its ruling on whether the company must do more structural testing. MGM said the building poses a safety risk and must be demolished as soon as possible.
The Harmon Hotel is a joint project with Dubai World and was intended to open with 46 stories in 2009 as part of the $8.5 billion CityCenter development. Construction was halted at 26 floors after inspectors found flaws in steel reinforcements.
A trial is set for 2014 to decide whether MGM or contractor Perini Building Co. is responsible for $500 million in damage claims.
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Source: http://www.nbcnews.com/travel/itineraries/mgm-asks-quick-decision-flawed-vegas-hotel-1B8290980
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